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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are typically focused on practical aspects of the research design, like recruitment and consent as well as adherence to the use of commonly available equipment.

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The developer is known for its visually stunning slot machines, which attract players with their bright colors and captivating designs. They use advanced graphics to create a thrilling gameplay that will take players on an exciting journey. The games are tested for fairness and rely on the Random Number Generator to ensure random outcomes. Their mobile compatibility makes them ideal for players who are on the move.

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While Pragmatic Play is known for its slot machines, they also offer table games such as Bitcoin baccarat and Roulette. They have over dozen licensed games, and their software is known for its security and reliability. Their games are available in several languages and offer various betting options including live dealer tables.

Bonus rounds


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Pragmatic Software, a software firm, offers a variety of casino games on online gambling platforms. Pragmatic's iGaming solutions are used by the most reputable operators as well as casinos that are located in the land. The company offers front-end website design tools, analysis and promotions, marketing security payment systems, customer support, and bug reporting. In addition, the company provides its players a safe and secure environment with high-quality graphics as well as games.

The company has a large collection of games available to play demo versions of. It allows players to test out new games without having to log in or signing up. These games can be played instantly and give players an authentic casino experience. They are available on desktop, mobile devices, and tablets.

The company has a strong reputation among players due to its innovative reward systems and mobile-first approach. Its iGaming solutions include high-quality graphics and a fast-paced game. Pragmatic's Bingo games are a hit with players because of their unique rewards system. It is a lot more efficient than the traditional 90-ball bingo game. Additionally to that, the games of the company include a lucrative bonus feature that can bring you thousands of dollars in real cash. It's worth trying out the game to see if it suits your preferences. The company has plenty of games to pick from, including a complete range of progressive jackpots. This is a great opportunity to increase your earnings potential and keep you entertained for hours.

RTP

Pragmatic Play is one of the leading iGaming providers and offers players a huge portfolio of slot games. Certain of these games feature high RTPs that help players maximize their potential to win. Many of the company's games also have mobile compatibility which makes them perfect for use on tablets and smartphones. Some of these games come with a bonus game that allows players to win free spins.

The company's latest release Gates of Olympus takes players to the world of the ancient Greek gods, where Zeus oversees the action. This high-volatility slot game has the Pay Anywhere option that pays players if they get 8 or more identical symbols anywhere in the reels. It also includes an extremely lucrative Free Spins feature with multipliers that can go up to 500x the amount bet.

Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which employed various investigators and participants from various geographical areas. This kind of heterogeneity is necessary for practical trials to be valid, and it also reduces the chance of bias in the results. However, too much heterogeneity can result in problems with the design of the trial.

Pragmatic Play, a major player on the live casino market offers a variety of classic table games, including Blackjack and Roulette. The live studios of Pragmatic Play in Romania and Malta provide customers with an authentic gaming experience and a wide selection of virtual betting options. The company has also created numerous interactive game shows that make online gambling fun. Some of these shows have live hosts, whereas others are hosted by famous personalities from the industry.

Mobile compatibility

Pragmatic Play is a relatively new player in the online casino industry however, it has earned a name by offering mobile-friendly slots. Their games are optimized for mobile devices and run on HTML5 technology. They are also regulated and certified by respected gaming authorities, ensuring fairness and transparency. This is a good indicator for players because it indicates that the games have been thoroughly tested and verified to ensure randomness and unbiased results of every round.

Pragmatic Play offers not only mobile-friendly slot machines but also tables games and live casinos. The company is licensed and regulated by several authorities that include the Malta Gaming Authority and UK Gambling Commission. Its games are backed by the latest encryption technology and the security team is always on hand to help players solve any issues they may have.

Pragmatic Play's slot games are a hit for both newbies and seasoned players. They have modern graphics and traditional themes. Many of them have progressive jackpots as well as numerous bonus rounds and paylines. They aren't volatile, so you will have a lengthy gaming experience.

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Legality

Pragmatic Play has earned a reputation for providing top-quality games and an outstanding user experience. Its software is accessible on mobile devices and in multiple languages. It has established itself as one of the top gaming platforms in the casino industry despite its relative youth. The most recent releases include Wolves 5 reel video slot with a healthy RTP and stunning graphics. Other notable titles include Wolf Gold and Chilli Heat.

Pragmatic trials are designed to replicate real-life settings and achieve maximum external validity. They are typically commissioned by practitioners and policy makers to aid in their decision-making. They can also be used to determine the causality of an intervention and its results. However, they should not be used to substitute for explanatory studies.

The pragmatism concept is controversial, and there are doubts about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 suggested an distinction between explanation-based studies, which prove the physiological hypothesis or clinical hypothesis, as well as pragmatic trials, which inform the decision-making process for policy and practice. They also proposed a framework called PRECIS for pragmatic trials.2 The tool was designed to define the elements of a pragmatic research study, including recruitment, design, delivery of the intervention and its follow-up.

The number of pragmatic trials is growing. A recent Medline search using the words pragmatic and naturalistic, which was restricted to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This indicates that the health sciences community is becoming increasingly sensitized to the issue of pragmatics. It is important to remember that the majority of studies were conducted in primary-care settings.

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