Before the little blue pill became known as Viagra Malaysia, it was first conceived of and studied as a drug to treat high blood pressure and a type of heart disease called angina pectoris. But in 1989, British scientists noticed that their drug, sildenafil citrate, also had a curious side effect: it helped men with erectile dysfunction (ED). Pharmaceutical giant Pfizer patented the drug and sold it as Viagra in 1998, and it has become one of the most popular prescription medications for men around the world to treat ED. Viagra works by inhibiting the phosphodiesterase type 5 (PDE5) enzyme, which is responsible for controlling blood flow to the penis. This makes it easier for blood to reach the erectile tissue in the penis and helps produce an erection when sexual stimulation occurs. Viagra only becomes effective once sexual arousal has occurred, so it is typically taken about an hour before sex on an empty stomach.

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