H. pylori Vaccine Development Services The prevalence of H. pylori infection is high in the population. Typically, triple therapies and quadruple therapies are used to treat H. pylori infection. However, due to the high rate of spontaneous mutation of H. pylori, treatment of H. pylori infection with antibiotics can easily cause antibiotic resistance in H. pylori, which makes H. pylori eradication difficult. Therefore, vaccination against H. pylori infection has become the most important strategy to reduce the prevalence of H. pylori infection in the population.