Sildalist is a medication that combines two active ingredients: Sildenafil Citrate and Tadalafil. These components are used to treat erectile dysfunction (ED) in men. Sildalist is available in two strengths: sildalist 120mg. And Sildalist 140 mg Here's a detailed look at both ingredients and their role in Sildalist: Sildenafil Citrate: This is a well-known medication for treating erectile dysfunction. It works by inhibiting the action of the enzyme phosphodiesterase type 5 (PDE-5) in the body. PDE-5 is responsible for breaking down cyclic guanosine monophosphate (cGMP), a substance that relaxes smooth muscles and increases blood flow to certain areas of the body, including the penis. By inhibiting PDE-5, Sildenafil Citrate helps maintain higher levels of cGMP, leading to improved erectile function. Tadalafil: Similar to Sildenafil, Tadalafil is also a PDE-5 inhibitor used in treating ED. It helps relax the blood vessels in the penis, allowing more blood to enter and leading to an erection in response to sexual stimulation. Tadalafil is known for its longer duration of action compared to Sildenafil, extending the window of effectiveness.