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Leptin is a polypeptide hormone produced by fat cells in your body. Leptin hormone sends signals to your brain to decrease food intake and increase energy expenditure. Researchers are currently studying leptin and weight loss to understand how the hormone can help you lose weight. Leptin: Definition and uses for weight loss Your body produces many hormones that help you eat the right amount of food and maintain a healthy weight. Leptin is one of them. Leptin hormone is produced by your fat cells. When you have more fat, you produce more leptin. After your fat cells make leptin, it travels through the bloodstream to the hypothalamus. The hypothalamus is the part of your brain that regulates hunger, thirst, mood, and many other physical functions. When the leptin receptors in the hypothalamus interact with the hormone leptin, they send satiety signals to your brain that it has enough stored energy (fat). Energy stores are fat stores. Leptin is the way your body tells your brain to stop eating because it has all the stored energy (fat) it needs. Leptin has other functions in your body, but most dieters and healthy eaters are more interested in leptin for weight loss. Researchers began studying leptin in the 1990s and are continuing to investigate ways the hormone can help you lose weight and maintain pounds. Leptin resistance and obesity An important area of research that scientists have studied is leptin resistance . Some researchers believe that leptin resistance is the reason why people who are obese have a harder time eating less and losing weight. So how does leptin resistance work? The researchers aren't exactly sure, but they do know that leptin levels are higher in people who are obese. But despite the higher levels of the hormone, satiety signals don't seem to work the same way they do in thinner people. In short, the messages that tell your brain to stop eating and start burning more calories don't work as they should even if your leptin levels are high. But the idea of leptin resistance is controversial because scientists don't know exactly how the hormone interacts with other factors. There are many other hormones for appetite and hunger that play a role in what you eat and how much you eat. The researchers also know that there are other things that affect your food intake, such as food odors, food tastes, habits, reward systems, and even cultural traditions. Therefore, they cannot say with certainty that leptin resistance causes obesity. Leptin supplements for weight loss If you're trying to lose weight, you've certainly seen ads for leptin supplements online or in magazines. The ads are intended to help you increase your leptin levels or correct your leptin resistance. But these pills do not contain the hormone leptin. Most diet pills simply contain trendy ingredients, like green tea or fiber, which can help you feel full or burn more calories. Since researchers don't fully understand leptin and leptin resistance, it is unlikely that an online company has deciphered it. If you suspect that your leptin levels are inactive or that you have leptin resistance, your best option is to talk to your doctor about hormonal tests or other treatments to help you lose weight.


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