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Patients at increased risk may be prescribed opioids such as OPANA ER, but use in such patients necessitates intensive counseling about the risks and proper use of OPANA ER along with intensive monitoring for signs of addiction, abuse, and misuse. This medicine should not be used to treat pain that you only have once in a while or "as needed". When oxymorphone is used for a long time, it may become habit-forming (causing mental or physical dependence).

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