Zavamet 1000Tablet 10's is a combination drug of Vildagliptin (DPP-4 inhibitor) and Metformin (Biguanides) belongs to the class of anti-diabetic. Type 2 diabetes mellitus used to be known as 'non-insulin-dependent diabetes mellitus (NIDDM)' or 'maturity-onset diabetes. Type 2 diabetes develops if the body does not produce enough insulin or when your body's insulin does not work as well as it should. It can also develop if the body produces too much glucagon. Insulin is a substance which helps to lower the level of sugar in your blood, especially after meals. Zavamet 1000 Tablet 10's is another substance which triggers the production of sugar by the liver, causing the blood sugar to rise. The pancreas makes both of these substances. Zavamet 1000 Tablet 10's helps to control the blood sugar level. It works by making the pancreas produce insulin and less glucagon (effect of vildagliptin) and also by helping the body to make better use of the insulin it has (effect of metformin). You must continue following the diet and exercise recommended for you whilst on treatment with Zavamet 1000 Tablet 10's. Zavamet 1000 Tablet 10's is not a substitute for insulin. It is not used to treat type 1 diabetes (where your body does not produce insulin) or diabetic ketoacidosis. Zavamet 1000 Tablet 10's should be taken with food to avoid an upset stomach. Zavamet 1000 Tablet 10's should be taken at the same time of the day each time for best results. For better advice, your doctor will decide what dose should be taken, which can change quickly depending on your condition. The most common side effect of Zavamet 1000 Tablet 10's is hypoglycemia (low blood glucose levels) characterised by dizziness, sweating, palpitations, hunger pangs, dry mouth and skin etc. So, to avoid hypoglycemia, you should not miss meals and also should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms. Uses of Zavamet 1000 Tablet 10's Type 2 Diabetes Mellitus Medicinal Benefits Zavamet 1000 Tablet 10's helps your pancreas produce more insulin, effectively utilise insulin, and decrease the excess sugar that your liver makes. It helps control the rise of blood sugar levels in your body after a meal. Zavamet 1000 Tablet 10's plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing. Directions for Use Zavamet Swallow it as a whole with water; do not crush, break or chew it. Side Effects of Zavamet 1000 Tablet 10's Low blood sugar,Nausea,Headache,Shaking or quivering,Vomiting,Diarrhoea,Abdominal pain,Loss of appetite,Joint pain,Tiredness,Constipation,Swollen hands, Ankle or feet (oedema).